Biomanufacturing

Biomanufacturing produces a wide range of biobased products for the emerging global bioeconomy. Biomanufacturing begins with bioprospecting – the discovery and commercialization of new products based on biologic resources. Biomanufacturing requires knowledge and methods from many scientific disciplines including biology, microbiology, biotechnology, chemistry, physics, engineering and technology. It includes genetic engineering and metabolic engineering plus various cell and tissue culture technologies.

Biomanufactured products range from biopharmaceuticals to industrial enzymes, human tissues and replacement organs, biofuels, ‘green’ chemicals and green products to replace those derived from petroleum. The application of biotechnology to industrial manufacturing is not only transforming how we develop and produce products, it's also generating new ideas - such as using microalgae to scrub power plant effluent gases and process water while making biofuels to help run the power plant at the same time. Another example is anaerobically turning cow manure and other wastes into gases to make electricity.

Every job in a biomanufacturing enterprise must combine in a unified effort to build quality into each phase of making the product. Everyone involved shares the same goal: achieve the highest quality product on a consistent basis. Commonly held skill standards and protocols establish and maintain this state of thorough control. The Food and Drug Administration’s current Good Manufacturing Practices (cGMP), outlined in CFR 210 and 211, are used to create repeatable standard operating procedures (SOPs) that can be validated to make sure manufactured products always have consistent quality. Teams develop methods for effectively monitoring production performance. Together, they analyze samples to evaluate each step and continually improve goal attainment.

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Cell culture technicians grow living cells in culture flasks, bioreactors, plates and other kinds of containers.  The types of cells they grow can come from plants or animals.  Sometimes cell culture technicians start cultures directly from tissues such as umbilical cords or tumor biopsies.   ... Read more

Chemistry Quality Control teams perform daily bench work. To meet required levels of quality, they test all raw materials, packing materials, and finished products according to standard operating procedures (SOPs). Technicians operate sophisticated test equipment and use advanced computers to ... Read more

Workers in bioscience facilities and research environments can be exposed to a variety of chemical, biological or physical hazards as they perform daily tasks. Government agencies strictly enforce regulations related to workplace safety, health and the environment. Environmental Health and ... Read more

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Lena Bengtsson graduated from the Biotechnology program at City College of San Francisco where she received  certificates in Bio-manufacturing, Biotechnology, Biotechnology Lab Assistant, Stem Cell Technology, Completed a CIRM funded Stem Cell Trainee program and received an Associates Degree in Biotechnology.  She currently works for the University of California, San Francisco as a Staff Research Assistant.Read more

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Learn how biomanufacturing is used in producing drugs.

We thank ATETV for permission to use this video.Read more

Many biotechnology products are grown in living cells.

We thank ATETV for permission to use this video.Read more

Learn how biotechnology and biomanufacturing are used in producing drugs.

We thank ATETV for permission to use this video.Read more